30-175

Estudio experimental de la consolidación de fracturas en la desnutrición proteica.Utilización de calcitonina en ratas desnutridas

Experimental study on the consolidation of fractures. The role of calcitonin in rats with restriction protein diet

R. GUARNIERO, T. E. P. DE BARROS, C. A. DE FREITAS, C. JUNQUEIRA, A. PEDRINELLI, M. DE ANDRADE Facultad de Medicina de la Universidad de Sao Paulo. Sao Paulo. Brasil.
Recepción:
06/11/2008
Aceptación:
06/11/2008
Publicación:
06/11/2008


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Resumen (ES)

The authors studied the role of Calcitonin in the consolidation of experimental fractures produced in the left tibiae of 65 adult Albino rats. The animals were divided in four groups: Group A: 20 animals on a normal diet, receiving Calcitonin 5 U/kg body weight, intramuscular daily; Group B: 20 animals fed on a no-protein diet and receiving Calcitonin in the same dosage as Group A and daily; Group C: Control group- 15 animals on normal diet and without any medication; and Group D: Control group- 10 animals on no-protein diet and without any medication. To the components of the non-protein diet was added maize starch (MaizenaR ) which was the calory-source. The fractures were standardized to meet the conditions of the experiment such as fractures should be similar concerning both their localization in the diaphyses and their shape and trace; tibiae were chosen for our study due to the readiness with which handmade fractures can be produced. In all groups the animals were killed three weeks after the fractures had been carried out. During this interval, Correspondencia: Dr.

Palabras clave (ES):

Reparación
Nutrición
Experimental
Consolidación
Fractura
Hipoproteinemia

Resumen (EN)

The authors studied the role of Calcitonin in the consolidation of experimental fractures produced in the left tibiae of 65 adult Albino rats. The animals were divided in four groups: Group A: 20 animals on a normal diet, receiving Calcitonin 5 U/kg body weight, intramuscular daily; Group B: 20 animals fed on a no-protein diet and receiving Calcitonin in the same dosage as Group A and daily; Group C: Control group- 15 animals on normal diet and without any medication; and Group D: Control group- 10 animals on no-protein diet and without any medication. To the components of the non-protein diet was added maize starch (MaizenaR ) which was the calory-source. The fractures were standardized to meet the conditions of the experiment such as fractures should be similar concerning both their localization in the diaphyses and their shape and trace; tibiae were chosen for our study due to the readiness with which handmade fractures can be produced. In all groups the animals were killed three weeks after the fractures had been carried out. During this interval, Correspondencia: Dr.

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