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Infección periprotésica en pacientes ancianos tratados mediante hemiartroplastia de cadera tras fractura intracapsular ¿Es el uso de cemento impregnado con altas dosis de antibiótico es un factor asociado a su disminución?.

Periprosthetic infection in elderly patients treated by hip hemiarthroplasty after intracapsular fracture. Is the use of cement impregnated with high doses of antibiotics a factor associated with its reduction?

NOVOA-PARRA CD 1,2, HURTADO-CEREZO J 1, MORALES-RODRÍGUEZ J 1, RODRIGO-PÉREZ JL 1, BLAS-DOBÓN JA 1, PELAYO DE TOMÁS JM 1. 1 SERVICIO DE CIRUGÍA ORTOPÉDICA Y TRAUMATOLOGÍA. HOSPITAL UNIVERSITARIO DR. PESET. VALENCIA, ESPAÑA. 2 SERVICIO DE CIRUGÍA ORTOPÉDICA Y TRAUMATOLOGÍA. HOSPITAL DE DENIA, ALICANTE, ESPAÑA.
Recepción:
03/11/2020
Aceptación:
03/11/2020
Publicación:
04/11/2020

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Resumen (ES)

Objective: to study whether the use of cement with a high dose of antibiotics is a factor associated with a lower infectionrate in hip hemiarthroplasty after femoral neck fracture.Material and methods: a retrospective cohort study of 144consecutive patients treated surgically for a cervical hip fracture with cemented hip hemiarthroplasty between February2015 and February 2017. In 88 (61.1%) high dose antibiotic cement was used, defined as a concentration ≥ 5% of thetotal weight (Group 1) and in 56 (38.9%) cement without antibiotics was used (Group 2). The primary outcome variablewas periprosthetic infection.Results: there were 2 (1.38%) infections that were classified as deep, both in group 1. One ofpatients had a superficial infection in group 2. We did not find differences in the rate of infections between the two groups.Among the intra-surgical complications, we found two failures of the cement-prosthesis interface (non-adherence of thecement to the stem at the end of the setting time), both cases occurred in group 1. There was no allergic or toxic reaction.The mean survival time of all operated patients was 2.7 years (95% CI: 2.4-2.9) at the end of follow-up. We found nodifferences in survival when stratified by the use or not of antibiotics in cement, p = 0.874.Conclusion:In our experience, inpatients undergoing hip hemiarthroplasties the use of cement with a high dose of antibiotic is not associated with lowerinfection rate when intravenous antibiotic prophylaxis is correct.

Palabras clave (ES):

Antibióticos
Infección;
de
cadera;
Prótesis
Hemiartroplastia;
Cemento
Óseo
con

Resumen (EN)

Objective: to study whether the use of cement with a high dose of antibiotics is a factor associated with a lower infectionrate in hip hemiarthroplasty after femoral neck fracture.Material and methods: a retrospective cohort study of 144consecutive patients treated surgically for a cervical hip fracture with cemented hip hemiarthroplasty between February2015 and February 2017. In 88 (61.1%) high dose antibiotic cement was used, defined as a concentration ≥ 5% of thetotal weight (Group 1) and in 56 (38.9%) cement without antibiotics was used (Group 2). The primary outcome variablewas periprosthetic infection.Results: there were 2 (1.38%) infections that were classified as deep, both in group 1. One ofpatients had a superficial infection in group 2. We did not find differences in the rate of infections between the two groups.Among the intra-surgical complications, we found two failures of the cement-prosthesis interface (non-adherence of thecement to the stem at the end of the setting time), both cases occurred in group 1. There was no allergic or toxic reaction.The mean survival time of all operated patients was 2.7 years (95% CI: 2.4-2.9) at the end of follow-up. We found nodifferences in survival when stratified by the use or not of antibiotics in cement, p = 0.874.Conclusion:In our experience, inpatients undergoing hip hemiarthroplasties the use of cement with a high dose of antibiotic is not associated with lowerinfection rate when intravenous antibiotic prophylaxis is correct.

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