recurrences following CCH treatment of Dupuytren’s disease are controversial andsometimes normal pathological anatomy is distorted. Our study aims to evaluate the presence of possible alterationsof the disease at pathological level on samples of recurrence of Dupuytren’s disease (CCH vs fasciectomy).Methods: prospective, blind study for pathological and statistical analysis of patients who underwent fasciectomydue to recurrence of Dupuytren’s disease after previous treatment with collagenase or previous fasciectomy.Pathological study with H / E and immunohistochemistry. Results: a total of 8 patients were included (4 withprevious treatment with CCH and 4 with fasciectomy). There were no significant differences in anatomopathologicalor inmonuhistochemical analysis. Conclusions: histologically, recurrences of Dupuytren Disease afterfasciectomy or collagenase treatment are indistinguishable. The presentation of macroscopic forms other thanthose seen in fasciectomy is possible.

recurrences following CCH treatment of Dupuytren’s disease are controversial andsometimes normal pathological anatomy is distorted. Our study aims to evaluate the presence of possible alterationsof the disease at pathological level on samples of recurrence of Dupuytren’s disease (CCH vs fasciectomy).Methods: prospective, blind study for pathological and statistical analysis of patients who underwent fasciectomydue to recurrence of Dupuytren’s disease after previous treatment with collagenase or previous fasciectomy.Pathological study with H / E and immunohistochemistry. Results: a total of 8 patients were included (4 withprevious treatment with CCH and 4 with fasciectomy). There were no significant differences in anatomopathologicalor inmonuhistochemical analysis. Conclusions: histologically, recurrences of Dupuytren Disease afterfasciectomy or collagenase treatment are indistinguishable. The presentation of macroscopic forms other thanthose seen in fasciectomy is possible.