Modificaciones histoquímicas de la fisis proximal tibial de ratas sometidas a stress emocional crónico.

In this paper 50 one month old male rats were used. 25 of them were controled and the rest was stressed by a modification of Bonfill's technique. After being sacrificedat 1, 2, 4, 8 and 12 weeks a histochemical study (Alelan Blue technique) was made on the proximal growth pIate of the tibias.Results showed that the epiphyseal plates of stressed animals had very little avidity for Aleian Blue from the beginning to the end of the experiment. Initially controledanimals showed a high avidity which progressively decreased. Staining was very similar in both groups of animals at the twelfth week.It is suggested that stress causes an initial stop in the activity of proliferative condrocytes.This progressively recovers to become normal. Due to the time of decreased activity of growth plates, it is adviceable to avoid stressing situations in children with orthopaedic and traumatic troubles.

In this paper 50 one month old male rats were used. 25 of them were controled and the rest was stressed by a modification of Bonfill's technique. After being sacrificedat 1, 2, 4, 8 and 12 weeks a histochemical study (Alelan Blue technique) was made on the proximal growth pIate of the tibias.Results showed that the epiphyseal plates of stressed animals had very little avidity for Aleian Blue from the beginning to the end of the experiment. Initially controledanimals showed a high avidity which progressively decreased. Staining was very similar in both groups of animals at the twelfth week.It is suggested that stress causes an initial stop in the activity of proliferative condrocytes.This progressively recovers to become normal. Due to the time of decreased activity of growth plates, it is adviceable to avoid stressing situations in children with orthopaedic and traumatic troubles.