The authors carried out a bibliographic review about this neurotoxic diseasewith reference to epidemiological data, emphasizing the special socioeconomicfactors and therefore, its "geographic" presentation. The authors have studied the posiblepathogenic mechanismes, no definitively explained, and the relationship withanother neurotoxic syndromes brought about food legumes consumption. They havemade too an analysis with regard to utilization of lathyrogens on different experimentalmodels in basic research. They approach the managment considering preventer measuresand point out the caracteristic of neurologic and orthopaedic sequelae, and surgicalpossibilities.

The authors carried out a bibliographic review about this neurotoxic diseasewith reference to epidemiological data, emphasizing the special socioeconomicfactors and therefore, its "geographic" presentation. The authors have studied the posiblepathogenic mechanismes, no definitively explained, and the relationship withanother neurotoxic syndromes brought about food legumes consumption. They havemade too an analysis with regard to utilization of lathyrogens on different experimentalmodels in basic research. They approach the managment considering preventer measuresand point out the caracteristic of neurologic and orthopaedic sequelae, and surgicalpossibilities.